Knights of the Pain Table

A Camelot for Sufferers of Chronic Pain

New Lupus Medication, Benlysta, by Human Genome May be Breakthrough


Lupus is an autoimmune disease. The immune system attacks healthy cells in the tissues by mistake. This process can cause symptoms such as inflammation,  swelling,  pain, and damage to joints,  skin, kidneys,  blood,  the heart,  and lungs. Women tend to be more at risk.

Patients with lupus rely on immune suppressants and steroids to treat their disease, but these often have side effects.

Human Genome Sciences and GlaxoSmithKline have developed an experimental lupus treatment, which aims to suppress the immune system’s response to lupus.    This medicine called  “Benlysta” ( known generically as belimumab),   has proved effective in a large clinical trial and had only mild side effects.

This is exciting news,   as this is the first new treatment for the disease in more than 40 years.    Patients taking Benlysta had fewer disease flare-ups, fewer severe flare-ups, and a longer time between flare-ups.

The anticipated study data, from a clinical program called Bliss-76, showed a 10-milligram dose of Benlysta, plus therapy with steroids,  prompted an improvement in 43 percent of patients, compared with an improvement in only 33 percent of patients on the placebo end of the study.

Human Genome of Rockville, Md., and GlaxoSmithKline,   based in the U.K.,  plan to seek Food and Drug Administration regulatory approval in the first half of 2010.   It may reach the market by the second half of 2010.

These findings were reported at the 73rd Annual Scientific Meeting of the American College of Rheumatology.

We hope this treatment will help those who suffer with lupus.

Lady Sharon
Scribe of Camelot

Read more at the Washington Post

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6 Responses to “New Lupus Medication, Benlysta, by Human Genome May be Breakthrough”

  1. davenycity says:

    great blog thank you

  2. Very nice post. I just stumbled upon your blog and wanted to say that I’ve truly enjoyed surfing around your blog posts. After all I’ll be subscribing to your rss feed and I hope you write again very soon!

  3. Lady Sharon says:

    Thank you Lars 🙂

  4. Lady Sharon says:

    Hi Davenycity,

    I thank thee for stopping by Camelot. Please come by again.

    Lady Sharon

  5. Lady Sharon says:

    Dear Carlota,

    It is a pleasure to meet you. Thank you for your kind words. May your way be guided by peace Carlota.

    Lady Sharon